From Reuters, via a Medscape article earlier this week:
Thiazide diuretics, used to treat hypertension and cardiovascular disease, may increase the risk of cholecystitis, new study results suggest. There is evidence that thiazide treatment increases biliary cholesterol saturation, but studies evaluating its association with gallbladder disease have yielded mixed results. … The age-adjusted relative risk of cholecystectomy for thiazide users was 1.57. … To rule out a generic effect of diuretics on gallbladder disease, Dr. Leitzmann's group examined the association between furosemide diuretics and cholecystectomy risk. In this situation the multivariate relative risk was 1.05.
Fun fun fun! Enjoy your ongoing organ deterioration, kiddies. I know I will!
